Bgee: Gene Expression Evolution

New Bgee release 13 data are now available! Check out our new download page

Expression data retrieved for the gene family ENSFM00300000079128 - in Drosophila melanogaster

Query parameters
Species: Drosophila melanogaster
Gene family: ENSFM00300000079128
Data parameters
[?] [?]

Hide | TopAffymetrix

Affymetrix experiment E-GEOD-14371

Experiment name The foraging gene in Drosophila mediates metabolic as well as behavioral plasticity [E-GEOD-14371]
Source ArrayExpress
Experiment description The foraging gene in Drosophila, encoding PKG, is known for its importance as a natural variant affecting behavioral plasticity. Here, we demonstrate that it also affects metabolic plasticity: Rovers show a greater response to changes in their food environment than do sitters. Using metabolic profiling, we define foraging- and food-dependent changes in metabolites indicating that Rover store energy predominantly as lipids, whereas sitter variants store it as carbohydrates, Such changes are reflected in gene expression patterns, indicating an influence of foraging on regulators of insulin signaling. Combining for alleles with mutants of positive insulin signaling regulators makes Rover responses sitter-like, but does not change sitter responses. Collectively these findings suggest that the effect on metabolic plasticity of foraging works through the insulin signaling pathway. Keywords: stress response, comparative genomic hybridization, genotype by environment Design: 3 genotypes x 2 treatments x 3 replicates. Treatments were leaving flies on lab food (control) or food-depriving them overnight with access to water. Three genotypes differed in foraging alleles: Rovers are homozygous for[R] (strain: BB), sitters homozygous for[s] (strain: ee, mutant sitters homozygous for[s2] (strain:s2) . Adult flies were 6-7 days post emergence. Three samples of equal numbers of male and females were collected per combination, frozen in liquid nitrogen, and heads were sieved for RNA extraction. This Gene by Environment design tests how presence or absence of food for a short period (overnight) affects gene expression in different foraging genotypes.
Chips
  • Chip ID: GSM359354_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM359352_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM359349_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: low quality
  • Chip ID: GSM359350_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM359351_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM359358_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM359353_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM359357_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: low quality
  • Chip ID: GSM359348_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM359359_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM359356_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM359355_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality

Affymetrix experiment E-GEOD-4531

Experiment name Transcription profiling of Drosophila melanogaster whole heads after treatment with ethanol vapour sampled at multiple time points vs controls to understand the molecular mechanisms underlying ethanol action [E-GEOD-4531]
Source ArrayExpress
Experiment description To better understand the molecular mechanisms underlying ethanol action we have developed an assay system to study sensitivity and fast and chronic tolerance to the sedative effects of ethanol. Flies developed fast ethanol tolerance after single exposure to 50% of ethanol vapor for 40 min. Flies can also develope chronic ethanol tolerance after 5x 40 min exposure to 50% ethanol vapor interspersed with 4x 80 min exposure to 10% ethanol vapor. We used microarray analysis to identify genes involved in the development of fast and chronic ethanol tolerance in Drosophila. More than 600 hundred genes were found to have changed their expression level in response to different ethanol treatment. Among these genes, Homer was picked for further study and is demonstrated that its expression in ellipsoid body is critical for the normal sensitivity and fast toleance to ethanol. Experiment Overall Design: Whole heads of 3 groups of Drosophila were separated for RNA extraction and hybridization on Affymetrix microarrays. These 3 groups of flies were treated with different ethanol treatment. Naive group of flies (GSM101531, GSM101532, GSM101533, GSM101534, GSM101535, GSM101536) received only 50 min of humidified air. Fast group of flies (GSM101537, GSM101538, GSM101539, GSM101540, GSM101541, GSM101542) received humidified air for 50 min followed by a single exposure of 50% ethanol vapor for 40 min. Chronic group of flies (GSM101543, GSM101544, GSM101545, GSM101546, GSM101547, GSM101548) ) received humidified air for 50 min followed by 5 exposures of 50% ethanol vapor for 40 min.
Chips
  • Chip ID: GSM101536_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000004 - Developmental stage ID: FBdv:00005336
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM101532_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000004 - Developmental stage ID: FBdv:00005336
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM101534_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000004 - Developmental stage ID: FBdv:00005336
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM101533_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000004 - Developmental stage ID: FBdv:00005336
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM101531_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000004 - Developmental stage ID: FBdv:00005336
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM101535_sample_table.txt - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000004 - Developmental stage ID: FBdv:00005336
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality

Affymetrix experiment E-MEXP-1099

Experiment name Transcription profiling of wild type and heterozygote and homozygote chico mutant Drosophila [E-MEXP-1099]
Source ArrayExpress
Experiment description comparison of wild type and heterozygote and homozygote chico mutants ( Clancy, et al. Extension of Life-Span by Loss of CHICO, a Drosophila Insulin Receptor Substrate Protein. Science 292 (5514), 104.) on Affymetrix Drosophila2 GeneChip. The flies (Drosophila melanogaster) are 7 day old adult females.
Chips
  • Chip ID: wt_r5 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: wt_r2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: wt_r4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: wt_r3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: wt_r1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment E-MEXP-1513

Experiment name Transcription profiling of Drosophila wild type, Nurf301 mutant and hop[Tum-1] mutant third instar larvae [E-MEXP-1513]
Source ArrayExpress
Experiment description Expression profile of wild-type and Nurf301 and hop[Tum-l] mutant Drosophila third instar larvae were compared
Chips
  • Chip ID: K4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005339 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: J4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005339 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: K2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005339 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: C3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005339 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: D3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005339 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: E4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005339 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment E-MEXP-152

Experiment name Transcription profiling of the response of adult Drosophila to oxidative and ER stress [E-MEXP-152]
Source ArrayExpress
Experiment description We used oligonucleotide microarrays to address the specificities of transcriptional responses of adult Drosophila to different stresses induced by paraquat and H2O2, two oxidative stressors, and by tunicamycin which induces an endoplasmic reticulum (ER) stress. Flies were tested 24 hours after exposure to continuous stresses induced by ingestion of paraquat, H2O2 or tunicamycin at concentrations leading to similar effects on viability. We used concentrations of 1% H2O2, 5mM paraquat and 12uM of tunicamycin which lead to negligeable mortality at 24 hours. A paraquat concentration of 15mM was also used for comparison with previous studies Both specific and common responses to the three stressors were observed and whole genome functional analysis identified several important classes of stress responsive genes. Within some functional classes, we observed large variabilities of transcriptional changes between isozymes, which may reflect unsuspected functional specificities.
Chips
  • Chip ID: C.2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: C.4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: C.3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: C.1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment E-MEXP-1594

Experiment name Transcription profiling of Drosophila 40 homozygous Raleigh lines to understand the genetic basis of complex traits in Drosophila [E-MEXP-1594]
Source ArrayExpress
Experiment description We used microarrays to assess whole genome transcript profiles of the 40 homozygous Raleigh lines to understand the genetic basis of complex traits in Drosophila
Chips
  • Chip ID: EA05066_30818_DROSO2_74 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31119_DROSO2_112 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30487_DROSO2_82 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31111_DROSO2_92 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31128_DROSO2_138 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30463_DROSO2_27 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31107_DROSO2_76 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30839_DROSO2_149 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30496_DROSO2_105 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30511_DROSO2_148 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31103_DROSO2_45 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30490_DROSO2_87 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30840_DROSO2_158 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: 365M1_59-A - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30834_DROSO2_129 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30515_DROSO2_157 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30465_DROSO2_29 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30466_DROSO2_32 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30509_DROSO2_146 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30790_DROSO2_14 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30480_DROSO2_64 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: 517M1_99-A - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31096_DROSO2_12 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30485_DROSO2_79 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30817_DROSO2_73 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31115_DROSO2_100 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30482_DROSO2_67 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30477_DROSO2_56 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30507_DROSO2_137 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30493_DROSO2_94 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30461_DROSO2_22 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31117_DROSO2_108 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30471_DROSO2_46 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31130_DROSO2_142 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30800_DROSO2_35 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30467_DROSO2_33 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30457_DROSO2_4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30816_DROSO2_72 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30791_DROSO2_15 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30838_DROSO2_144 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30484_DROSO2_78 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30506_DROSO2_135 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30797_DROSO2_26 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30474_DROSO2_51 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30501_DROSO2_118 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30805_DROSO2_49 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30481_DROSO2_66 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30456_DROSO2_1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30802_DROSO2_38 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: 306M2_20-A - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: 555M2_104-A - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31131_DROSO2_143 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31125_DROSO2_128 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31238_DROSO2_152 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31102_DROSO2_40 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30503_DROSO2_130 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31109_DROSO2_84 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30486_DROSO2_81 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31135_DROSO2_155 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31116_DROSO2_106 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30804_DROSO2_43 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31120_DROSO2_113 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30795_DROSO2_23 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30786_DROSO2_6 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30784_DROSO2_3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30841_DROSO2_159 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30833_DROSO2_127 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: 714M1_123-A - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31110_DROSO2_89 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30497_DROSO2_109 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30821_DROSO2_91 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30472_DROSO2_47 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31112_DROSO2_96 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30469_DROSO2_42 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30514_DROSO2_156 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30828_DROSO2_115 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30835_DROSO2_131 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30803_DROSO2_41 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30462_DROSO2_25 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30832_DROSO2_126 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30822_DROSO2_93 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30808_DROSO2_54 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30505_DROSO2_134 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30500_DROSO2_117 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30814_DROSO2_69 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31118_DROSO2_111 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31136_DROSO2_86-A - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: EA05066_30460_DROSO2_10 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: 304M2_16-A - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30831_DROSO2_122 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30792_DROSO2_17 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31127_DROSO2_136 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30824_DROSO2_101 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30464_DROSO2_28 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30491_DROSO2_88 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30787_DROSO2_9 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30820_DROSO2_83 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31099_DROSO2_21 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30801_DROSO2_37 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30459_DROSO2_8 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30806_DROSO2_50 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30458_DROSO2_7 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: EA05066_30785_DROSO2_5 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30807_DROSO2_52 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30495_DROSO2_103 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30836_DROSO2_139 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30502_DROSO2_125 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30789_DROSO2_13 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30819_DROSO2_80 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30794_DROSO2_19 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30470_DROSO2_44 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30810_DROSO2_60 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30811_DROSO2_61 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30475_DROSO2_53 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30783_DROSO2_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31106_DROSO2_71 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30499_DROSO2_114 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30476_DROSO2_55 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30809_DROSO2_57 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30815_DROSO2_70 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30796_DROSO2_24 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30492_DROSO2_90 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31108_DROSO2_77 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30813_DROSO2_68 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30830_DROSO2_120 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30837_DROSO2_140 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31113_DROSO2_98 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31129_DROSO2_141 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30799_DROSO2_34 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31134_DROSO2_153 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30479_DROSO2_62 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30793_DROSO2_18 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30504_DROSO2_132 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30494_DROSO2_95 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30468_DROSO2_36 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30483_DROSO2_75 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31100_DROSO2_31 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31237_DROSO2_121 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30510_DROSO2_147 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30488_DROSO2_85 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31239_DROSO2_150 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30473_DROSO2_48 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30823_DROSO2_97 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30825_DROSO2_102 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30508_DROSO2_145 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31124_DROSO2_124 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31132_DROSO2_151 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31126_DROSO2_133 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30513_DROSO2_154 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30478_DROSO2_58 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30827_DROSO2_107 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30812_DROSO2_63 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30798_DROSO2_30 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30829_DROSO2_119 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30842_DROSO2_160 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30498_DROSO2_110 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31101_DROSO2_39 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31121_DROSO2_116 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_30788_DROSO2_11 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_31105_DROSO2_65 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment E-MEXP-1817

Experiment name Transcription profiling of Drosophila wild type and Caliban (Clbn-1Q) knock out embryos [E-MEXP-1817]
Source ArrayExpress
Experiment description Comparison of wild type (Ore-R) and Caliban knockout (Clbn-1Q) embryonic mRNA.
Chips
  • Chip ID: C2_8-1-08_s1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005335
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: C3_8-1-08_s1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005335
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: C1_8-1-08_s1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005335
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment E-MEXP-2011

Experiment name Transcription profiling of Drosophila wild type and Nurf301 mutant third instar larvae [E-MEXP-2011]
Source ArrayExpress
Experiment description Comparison of wild-type and Nurf301 mutant third instar larvae. Nurf301 mutants that remove all Nurf301 isoforms (Null) or mutants that remove full-length Nurf301 isoforms (DeltaC) were used
Chips
  • Chip ID: WT_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: WT_3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: WT_1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment E-MEXP-2070

Experiment name Transcription profiling of Drosophila head and thorax from females mated with sex peptide null or sex peptide producing males [E-MEXP-2070]
Source ArrayExpress
Experiment description Comparison of females mated to males null for Sex-Peptide (SP0, Liu, H. and E. Kubli, Sex-peptide is the molecular basis of the sperm effect in Drosophila melanogaster. Proc Natl Acad Sci U S A, 2003. 100(17): p. 9929-33) or to control, Sex-Peptide producing, males. Comparisons were made at 3 and 6 hours after mating, in dissected Head-Thorax body parts.
Chips
  • Chip ID: CT3he1b1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003005 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: CT6he4b1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003005 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: CT3he2b3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003005 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: CT6he2b3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003005 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: CT6he1b2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003005 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: CT3he3b4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003005 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: CT3he4b2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003005 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: CT6he3b4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003005 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment E-MEXP-2125

Experiment name Transcription profiling of Drosophila wild type and Ada2b knock out L3 larvae synchronized to spiracle eversion [E-MEXP-2125]
Source ArrayExpress
Experiment description Effect of the Ada2b mutation on L3 larvae synchronized to spiracle eversion (compared to w1118)
Chips
  • Chip ID: LT_W1118_2_Droso2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00007005
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: LT_W1118_1_Droso2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00007005
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: LT_W1118_3_Droso2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00007005
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment E-MEXP-2510

Experiment name Transcriptional profiling of Drosophila melanogaster injection time course with Mycobacterium marinum, with vehicle alone, or uninjected. [E-MEXP-2510]
Source ArrayExpress
Experiment description Drosophila melanogaster (1) injected with 5000 CFU Mycobacterium marinum; (2) injected with vehicle alone (7H9 media); or (3) uninjected.<br>Three time-points after infection: 24 hours, 72 hours, 96 hours.<br>All samples are in triplicate (biological replicates).<br>Death occurs in this infection between 96 and 120 hours.<br>As described in Dionne et al Current Biology 16 (20): 1977-1985.
Chips
  • Chip ID: Dionne_G_Dros - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: Dionne_H_Dros - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: Dionne_I_Dros - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment E-MEXP-2580

Experiment name Transcription profiling of Drosophila early embryos and unfertized eggs to analyze mRNA decay patterns in early development [E-MEXP-2580]
Source ArrayExpress
Experiment description Comparison of expression profiles in early Drosophila embryos and unfertilised eggs (collection intervals: 30-60 min, 90-120 min and 150-180 min after egg laying). A complete summary file containing normalized data with FLYBASE CG gene identifiers, gene symbols and classifications can be found in E-MEXP-2580.additional.zip under the "Browse all available files" link
Chips
  • Chip ID: E1-2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005293
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: U2-3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005287
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: E1-1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005293
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: U1-1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005287
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: U2-1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005287
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: E1-4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005293
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: U1-4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005287
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: U1-2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005287
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: U2-4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005287
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: U3-4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005287
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: U1-3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005287
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: E1-3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005293
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: U2-2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005287
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: U3-2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005287
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment E-MTAB-379

Experiment name Transcription profiling by array of a Drosophila line selected for increased parasitoid resistance and control line during development [E-MTAB-379]
Source ArrayExpress
Experiment description Transcriptional profile of a selection line (selected for increased parasitoid resistance) and control line at seven time points during development (egg -2nd instar)
Chips
  • Chip ID: A67_42Cc - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A05_42Ce_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A09_23Cb_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A32_23Cd - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A12_50Ca_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A43_23Ca - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A24_5Cb_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005324
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: A64_50Ce - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A39_18Cb - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005335
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A63_18Cd - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005335
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A57_23Cc - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A46_5Ce - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005324
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A50_18Ce - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005335
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A18_50Cd_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A10_18Ca_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005335
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A23_18Cc_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005335
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A49_42Ca - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A55_5Cc - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005324
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: A30_50Cc - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A04_5Cd - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005324
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: A34_5Ca - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005324
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A62_66Cc - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A38_66Ce - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A52_50Cb - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A02_66Cd - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A15_66Ca_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A21_23Ce_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A28_42Cd - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A33_42Cb - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: A58_66Cb - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment E-MTAB-653

Experiment name Transcription profiling of Drosophila to investigate mutations affecting aggressive behavior [E-MTAB-653]
Source ArrayExpress
Experiment description Epistasis and pleiotropy are important features of the genetic architecture of quantitative traits, but are difficult to assess in outbred populations. We performed a diallel cross among Drosophila P-element mutations previously associated with hyper-aggressive behavior, and demonstrated extensive epistatic and pleiotropic effects on aggression, brain morphology, and genome wide gene expression. Epistatic interactions were often of greater magnitude than homozygous effects, and the topology of the epistatic networks varied among the traits. The transcriptional signature of the homozygous and double heterozygous genotypes derived from the six mutations implies a large mutational target size for aggressive behavior and evolutionarily conserved genetic mechanisms and neural signaling pathways affecting aggressive behavior. We used six mutant lines homozygous for a P-element insertion, the 15 possible transheterozygous combinations of the initial six lines and a control line. All lines were isogenic other than the P-element insert. three replicates were done for a total of 66 arrays
Chips
  • Chip ID: EA05066_33118_DROSO2_csb_3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_33116_DROSO2_csb_1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: EA05066_33117_DROSO2_csb_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment E-RUBN-2

Experiment name Systematic determination of patterns of gene expression during Drosophila embryogenesis [E-RUBN-2]
Source ArrayExpress
Experiment description Background: Cell-fate specification and tissue differentiation during development are largely achieved by the regulation of gene transcription. Results: As a first step to creating a comprehensive atlas of gene-expression patterns during Drosophila embryogenesis, we examined 2,179 genes by in situ hybridization to fixed Drosophila embryos. Of the genes assayed, 63.7% displayed dynamic expression patterns that were documented with 25,690 digital photomicrographs of individual embryos. The photomicrographs were annotated using controlled vocabularies for anatomical structures that are organized into a developmental hierarchy. We also generated a detailed time course of gene expression during embryogenesis using microarrays to provide an independent corroboration of the in situ hybridization results. All image, annotation and microarray data are stored in publicly available database. We found that the RNA transcripts of about 1% of genes show clear subcellular localization. Nearly all the annotated expression patterns are distinct. We present an approach for organizing the data by hierarchical clustering of annotation terms that allows us to group tissues that express similar sets of genes as well as genes displaying similar expression patterns. Conclusions: Analyzing gene-expression patterns by in situ hybridization to whole-mount embryos provides an extremely rich dataset that can be used to identify genes involved in developmental processes that have been missed by traditional genetic analysis. Systematic analysis of rigorously annotated patterns of gene expression will complement and extend the types of analyses carried out using expression microarrays.
Chips
  • Chip ID: embryo_tc_8_1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_8_4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_4_9 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_6_1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_4_4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_8_3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_6_9 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_8_9 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_4_3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_6_3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_4_1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: embryo_tc_6_4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment E-TABM-297

Experiment name Transcription profiling of drosophila embryos ectopically expressing or repressing Ladybird to investigate genes invlolved in muscle and heart formation [E-TABM-297]
Source ArrayExpress
Experiment description In order to identify Ladybird mesodermal and heart target genes, we decided to analyse the transcriptional profiling of embryos with a targeted gain and Loss of function approach. Embryos were collected at stages 11 to 15 of embryogenesis corresponding to the lb expression period. Homozygous ectopically expressing or repressing embryos were collected from a large scale cross of UAS-lbe or UAS-RNAi-lbe flies with 24B-Gal4 or Tin-Gal4 flies, in parallel to stage-matched control. Three independent collections were performed. Total RNA was extracted. Ectopically expression and reference samples were hybridized together on GeneChip Drosophila Genome array2. With this approach, we were able to dicover a repertory of genes involved in different aspects of muscle and heart formation showing a multi-step action of this family of identity genes.
Chips
  • Chip ID: CJ_5_3_Droso_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: CJ_5_1_Droso_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: CJ_5_2_Droso_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment E-TABM-441

Experiment name Transcription profiling of wild type and miR-309 cluster mutant Drosophila embryos at 0-1h and 2-3h of embryonic development [E-TABM-441]
Source ArrayExpress
Experiment description To investigate whether early zygotic miR-309 cluster miRNA expression might contribute to the down-regulation of maternal transcripts during the maternal to zygotic transition in Drosophila, we performed microarray analyses of control and miR-309 cluster mutant embryos at 0-1h and 2-3h of embryonic development. One-hour egg collections of w1118 and miR-309-6delta1 mutant flies at 25?C were either aged (2-3h sample) at 25?C or directly processed (0-1h sample). Six independent collections per genotype and time-point were performed. Using this approach, we found that maternal transcripts were stabilized in the miR-309 cluster mutant, indicating that the miR-309 cluster miRNAs are required for the down-regulation of these transcripts during the maternal to zygotic transition in Drosophila.
Chips
  • Chip ID: w1118_0-1h_3 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005290
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: w1118_0-1h_2 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005290
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: w1118_0-1h_1 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005290
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: w1118_0-1h_5 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005290
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: w1118_0-1h_6 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005290
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: w1118_0-1h_4 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005290
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality

Affymetrix experiment GSE10169

Experiment name Transcription profiling of Drosophila model of mitochondrial disease [GSE10169]
Source GEO
Experiment description Background: A point mutation in the Drosophila gene technical knockout (tko), encoding mitoribosomal protein S12, provokes a phenotype of respiratory chain deficiency, developmental delay and neurological abnormalities similar to those presented in many human mitochondrial disorders, as well as defective courtship behaviour. Results: Transcriptome-wide analysis of gene expression in tko25t mutant flies revealed systematic, compensatory changes in expression of genes connected with metabolism, including upregulation of lactate dehydrogenase and of many genes involved in the catabolism of fats and proteins, the TCA cycle and anaplerotic pathways feeding into it. Gut-specific enzymes involved in the primary mobilization of dietary fat and protein, as well as a number of transport functions, were strongly upregulated, consistent with the idea that OXPHOS dysfunction is perceived physiologically as a starvation for particular biomolecules. Many stress-response genes were also induced. Other changes may reflect a signature of developmental delay. There was also down-regulation of genes connected with reproduction, including gametogenesis, especially in females, and courtship behaviour in males. This might represent a programmed response to a mitochondrially generated starvation signal. Although human sexual behaviour is not known to respond to mitochondrial dysfunction, the underlying signaling pathway, if conserved, could influence many physiological processes in response to nutritional stress. Transcriptomic analysis suggested the possible involvement of the Akt1/sgg signaling pathway(s). Conclusions: The transformation of metabolism in response to mitochondrial dysfunction, including digestive and absorptive functions, gives important clues as to how novel therapeutic strategies for mitochondrial disorders might be developed. Experiment Overall Design: Crosses and maintenance: Inbreeding under stressful conditions inevitably results in the selection of compensatory alleles of many genes. In order to avoid such issues, and thus determine the global effects on gene expression of the tko25t mutation in a truly unselected and 'wild-type' background, we outbred tko25t over more than 10 generations by back-crossing to each of two commonly used wild-type strains, Canton S and Oregon R. Subsequent to this backcrossing, tko25t was maintained in each background using a balancer chromosome. These stocks were then used to generate a tko25t mutant F1 generation, by crossing virgin Canton S tko25t homozygous mutant females with Oregon R tko25t males. For comparison, we generated otherwise isogenic wild-type F1 progeny by crossing virgin Canton S wild-type females with Oregon R wild-type males. Experiment Overall Design: Samples: Both tko25t and wild-type Drosophila adult flies of both sexes were collected and aged to 1 day old prior to RNA extraction and hybridization on Affymetrix microarrays. We extracted RNA from 3 independent such crosses. Experiment Overall Design: Comparative analysis: Data analysis for each gene in the array compared each tko25t mutant RNA isolate with each wild-type RNA isolate from flies of the given sex, generating 9 comparative measurements, over which the statistical analysis was performed.
Chips
  • Chip ID: GSM257068 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005370
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM257069 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005370
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM257067 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005370
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE10264

Experiment name Transcription profiling of Drosophila Hr39 mutant females reveals the sf1-related nuclear hormone receptor hr39 regulates Drosophila female reproductive tract development and function [GSE10264]
Source GEO
Experiment description The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR5A1) controls reproductive development and regulates the transcription of steroid-modifying cytochrome P450 genes. We find that the SF1-related Drosophila nuclear hormone receptor HR39 is also essential for sexual development. In Hr39 mutant females, the sperm-storing spermathecae and glandular parovaria are absent or defective, causing sterility. Our results indicate that spermathecae and parovaria secrete reproductive tract proteins required for sperm maturation and function, like the mammalian epididymis and female reproductive tract. Hr39 controls the expression of specific cytochrome P450 genes and is required in females both to activate spermathecal secretion and repress male-specific courtship genes such as takeout. Thus, a pathway that, in vertebrates, controls sex-specific steroid hormone production, also mediates reproductive functions in an invertebrate. Our findings suggest that Drosophila can be used to model more aspects of mammalian reproductive biology than previously believed. Experiment Overall Design: Wild type and Hr39(04443) Spermathecae, Wild type and Hr39(04443) Reproductive Tract
Chips
  • Chip ID: GSM259202 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM259197 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE11231

Experiment name Transcription profiling of Drosphilia embryos shows the zinc finger protein Zelda plays a key role in the maternal to zygotic transition [GSE11231]
Source GEO
Experiment description In all animals, the initial events of embryogenesis are controlled by maternal gene products that are deposited into the developing oocyte. At some point after fertilization, control of embryogenesis is transferred to the zygotic genome in a process called the maternal to zygotic transition (MZT). During this time maternal RNAs are degraded and zygotic RNAs are transcribed1. A long standing question has been, what factors regulate these events? The recent findings that microRNAs and Smaugs mediate maternal transcript degradation brought new life to this old problem2,3, however, the transcription factors that activate zygotic gene expression remained elusive. A clue came from the finding that many early zygotic genes in Drosophila share a cis-regulatory heptamer motif, CAGGTAG and related sequences, collectively referred to as TAG-team sites4,5. We asked whether there was a dedicated transcription factor that interacts with these sites to activate early genes. Here we report the discovery of a zinc-finger protein, Zelda (Zld) that binds specifically to TAG-team sites, and is capable of activating transcription in transient transfection assays. Mutant embryos lacking zld are defective in the cellularization process, and fail to activate the transcription of many early zygotic genes involved in cellularization, sex determination, and dorsoventral patterning. Global expression profiling confirmed that Zld plays a key role in the activation of the early zygotic genome, and suggests that Zld may also play a role in maternal RNA degradation during the MZT since many RNAs are up-regulated in the absence of Zld. Experiment Overall Design: Total RNA samples were extracted from three replicate collections of 1-2 hr yw and M- zld embryos by TRIzol (invitrogen). A portion of the collected embryos was fixed and stained with DAPI; 90% were in nuclear cycles 8 to13. cDNA was prepared using the GeneChip HT One-Cycle cDNA Synthesis Kit (Manufactured by Invitrogen for Affymetrix) and labeled with the BioArray HighYield RNA Transcript Labeling Kit (Enzo). Labeled probes were hybridized to Drosophila Genome 2 Affymetrix arrays and processed by a GeneChip Fluidics Station 400. Data were acquired and normalized by the GeneChip Scanner 3000 and processed by the Affymetrix GeneChip Operating Software (GCOS). t-test analysis was performed on the data from three biological replicates.
Chips
  • Chip ID: GSM283123 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM283124 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM283122 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE11825

Experiment name Transcription profiling of Drosophila wild type and bap170;bap180 double mutant reveals two PBAP chromatin remodeling complex-specific subunits have distinct, redundant functions during development [GSE11825]
Source GEO
Experiment description Chromatin remodeling complexes control the availability of DNA binding sites to transcriptional regulators. Two distinct forms of the major SWI/SNF-related complex that have different activities in vitro can be distinguished by the presence of specific accessory subunits. In Drosophila, the core Brahma complex associates either with Osa to form the BAP complex, or with Bap170 and Bap180 to form the PBAP complex. Mutations affecting the core subunits have stronger developmental phenotypes than osa mutations; these differences could be due to PBAP complex activity . We have generated mutations in the genes encoding the PBAP-specific subunits Bap170 and Bap180 in order to study their functions in vivo. Bap180 is not essential for viability, but is required in ovarian follicle cells for normal eggshell development. Bap170 is necessary to stabilize the Bap180 protein; however, a mutant form that retains this function is sufficient for survival and fertility. The two subunits act redundantly to allow metamorphosis; using gene expression profiling of double mutants, we have found that the PBAP complex regulates genes involved in tissue remodeling and immune system function. Finally, we have generated mutants that lack Bap170, Bap180 and Osa in the germline to demonstrate that the function of the core Brahma complex in oogenesis does not require any of these accessory subunits. To study PBAP specific subunits Bap170 and Bap180 role in Drosophila melanogaster development Experiment Overall Design: Two males and two females for each genotype (wild type and bap170;bap180 double mutant) were processed at white prepupae stage (0 hour APF)
Chips
  • Chip ID: GSM298826 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005342
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM298823 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005342
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM298825 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005342
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM298824 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005342
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE12160

Experiment name Expression profiling of Hyperoxia-Tolerant Drosophila melanogaster [GSE12160]
Source GEO
Experiment description One of the critical substances that mammals highly regulate via the respiratory, cardiovascular and neurologic systems is O2. Both low and high O2 levels can induce major morbidities as well as mortality. Indeed, O2 has been often considered as both an elixir and a poison in humans. In current study, we have used an experimental selection approach to generate Drosophila strains that are tolerant to severe hyperoxic environment. Gene expression profiling is then applied to investigate the mechanisms underlying hyperoxia tolerance in the newly generated strains. 27 isogenic D. melanogaster Lines were pooled and following long-term selection over generations with increased oxygen level in the culture environment. The differences in gene expression were compared between adapted flies and generation matched naive controls by microarray.
Chips
  • Chip ID: GSM306111 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM306123 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM306124 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM306110 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM306121 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM306112 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM306109 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM306120 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM306107 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM306122 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM306119 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM306108 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE12477

Experiment name Transcription profiling of Drosophila follicle cells during oogenesis [GSE12477]
Source GEO
Experiment description Two-dimensional patterning of the follicular epithelium in Drosophila oogenesis is required for the formation of three-dimensional eggshell structures. Our analysis of a large number of published gene expression patterns in the follicle cells suggests that they follow a simple combinatorial code based on six spatial building blocks and the operations of union, difference, intersection, and addition. The building blocks are related to the distribution of inductive signals, provided by the highly conserved epidermal growth factor receptor and Decapentaplegic; (DPP) pathways. We demonstrate the validity of the code by testing it against a set of patterns obtained in a large-scale transcriptional profiling experiment. Using the proposed code, we distinguish 36 distinct patterns for 81 genes expressed in the follicular epithelium and characterize their joint dynamics over four stages of oogenesis. The proposed combinatorial; framework allows systematic analysis of the diversity and dynamics of two-dimensional transcriptional patterns and guides future studies of gene; regulation. Experiment Overall Design: RNA was isolated from hand dissected, stage 9-10 egg chambers. Five genetic backgrounds were profiled including: wild type, EGFR gain of function, EGFR loss of function, BMP gain of function, and BMP loss of function. Three biological replicates were hybridized for each pathway perturbation. The samples were split across two rounds of hybridization. Each round of hybridizations included three biological replicates for wild type: Experiment Overall Design: The first round included EGFR gof, EGFR lof, BMP gof, and wild type controls A1-A3 (GSM313514-16). For these 12 arrays the extraction, labeling, and hybridization steps were done in parallel. Experiment Overall Design: The second round included the BMP lof and wild type controls B1-B3 (GSM313517-19). For these 6 arrays, the extraction, labeling, and hybridization steps were done in parallel.
Chips
  • Chip ID: GSM313516 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004865 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM313514 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004865 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM313517 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004865 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM313519 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004865 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM313518 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004865 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM313515 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004865 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE12834

Experiment name Immunogenic males: a genome-wide analysis of reproduction and the cost of mating in Drosophila melanogaster females [GSE12834]
Source GEO
Experiment description In Drosophila melanogaster, mating radically transforms female physiology and behavior. Post-mating responses include an increase in the oviposition rate, a reduction in female receptivity, and an activation of the immune system . The fitness consequences of mating are similarly dramatic -females must mate once in order to produce fertile eggs, but additional matings have a clear negative effect. Previously, microarrays have been used to examine gene expression of females differing in their reproductive status with the aim of identifying genes influenced by mating. However, since only virgin and single mated females were compared, transcriptional changes associated with reproduction (under natural selection) and the effects of male-induced harm (under sexually antagonistic selection) cannot be disentangled. We partitioned these fundamentally different effects by instead examining the expression profiles of virgin, single mated and double mated females. We found substantial effects relating to reproduction and further effects that are only attributable to a second mating. Immune response genes dominate this male-induced harm effect indicating that the cost of mating may be due partly to this system's activation. We propose that both sexually antagonistic and natural selection have been important in the evolution of the innate immunity genes, thereby contributing to the sexual dimorphismand rapid evolution at these loci. Keywords: Female response to mating Female flies were flash frozen in liquid nitrogen either as virgins or 6 hours after mating and stored at -80 C until RNA extraction was performed (not more than 2 days). 8 whole flies -randomly selected within each treatment- were pooled for each extraction. Total RNA was extracted using Trizol (Invitrogen) and purified with an RNeasy Mini Kit (Qiagen). RNA quantity and quality was checked with an Agilent Bioanalyzer. According to the manufacturer's instructions, samples were prepared and hybridized to Affymetrix GeneChip Drosophila Genome 2.0 (Affymetrix, Santa Clara, CA, USA) by the Uppsala Array Platform (Uppsala, Sweden). Each experimental treatment consisted of 4 independent RNA extractions and hybridizations, giving a total of 12 arrays.
Chips
  • Chip ID: GSM322186 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322182 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322183 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322192 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322181 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322185 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322184 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322190 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322191 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322189 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322187 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM322188 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE14517

Experiment name Transcription profiling of Drosophila deficiency hemizygotes and a duplication hemizygote reveals buffering of segmental and chromosomal aneuploidies in Drosophila melanogaster [GSE14517]
Source GEO
Experiment description Chromosomal instability which involves deletion and duplication of chromosomes or chromosome parts is a common feature of cancers, and deficiency screens are commonly used as a method to find genes involved in different biological pathways. Still, how gene expression from whole chromosomes or large chromosomal domains is affected by deficiencies, duplications or chromosome loss is largely unknown. Using expression microarrays of deficiency hemizygotes and a duplication hemizygote we show that expressed genes are significantly buffered when present in a deficiency hemizygote and that the buffering effect is general and not mainly caused by feedback regulation of individual genes. Differentially expressed genes are in general better buffered than ubiquitously expressed genes when present in one copy. When present in three copies, differentially expressed genes are in general less buffered than ubiquitously expressed genes. Furthermore, we show that the 4th chromosome is compensated in response to dose differences. Our results suggest that general mechanisms exist to stimulate and to repress gene expression of aneuploidy regions and on the 4th chromosome this compensation is mediated by POF (Painting of Fourth). Experiment Overall Design: We prepared total RNA from flies heterozygous for three different deletions, Df(2L)J-H, Df (2L)ED4470, Df(2L)ED4651, flies heterozygous for the duplication Dp(2;2)Cam3 and flies with only one chromosome 4, or three copies of the 4th chromosome, as well as from wild type control flies. Three biological replicates of all genotypes were prepared.
Chips
  • Chip ID: GSM362920 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM362918 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM362919 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE14531

Experiment name Transcription profiling of Drosophila dHNF4 null mutant larvae fed or starved for 24h [GSE14531]
Source GEO
Experiment description We show that dHNF4 null mutant larvae are sensitive to starvation. Starved mutant larvae consume glycogen normally, but retain lipids in their midgut and fat body, and have increased levels of long chain fatty acids, suggesting that they are unable to efficiently mobilize stored fat for energy. HNF4 dependent transcripts were identified under fed and starved conditions. Microarray studies indicate reduced expression of genes that control lipid catabolism and -oxidation. Late second instar control and HNF4 mutant larvae were collected and fed or starved for 24 hours, and then RNA was isolated for analysis. Taken together, our results support a feed-forward model for dHNF4, in which fatty acids released from triglycerides activate the receptor, inducing enzymes that drive fatty acid oxidation for energy production. Experiment Overall Design: Staged late second instar control larvae that were transheterozygous for precise excisions of the EP2449 and KG08976 P-elements, and dHNF4D33/dHNF4D17 mutant larvae, were either fed or starved for 24 hrs in a 55mm petri dish containing Whatman paper soaked with PBS. RNA was extracted from the apparently healthy animals that molted to the third instar using Trizol (Gibco) and purified on RNAeasy columns (Qiagen). All samples were prepared in triplicate to facilitate subsequent statistical analysis. Probe labeling, hybridization to Affymetrix GeneChip Drosophila Genome 2.0 Arrays.
Chips
  • Chip ID: GSM363632 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM363633 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM363634 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE14981

Experiment name Distinct Mechanisms Underlying Tolerance to Intermittent and Constant Hypoxia in Drosophila melanogaster [GSE14981]
Source GEO
Experiment description Background: Constant hypoxia (CH) and intermittent hypoxia (IH) occur during several pathological conditions such as asthma and obstructive sleep apnea. Our research is focused on understanding the molecular mechanisms that lead to injury or adaptation to hypoxic stress using Drosophila as a model system. Our current genome-wide study is designed to investigate gene expression changes and identify protective mechanism(s) in D. melanogaster after exposure to severe (1% O2) intermittent or constant hypoxia. Methodology/Principal Findings: Our microarray analysis has identified multiple gene families that are up- or down-regulated in response to acute CH or IH. We observed distinct responses to IH and CH in gene expression that varied in the number of genes and type of gene families. We then studied the role of candidate genes (up-or down-regulated) in hypoxia tolerance (adult survival) for longer periods (CH-7 days, IH-10 days) under severe CH or IH. Heat shock proteins up-regulation (specifically Hsp23 and Hsp70) led to a significant increase in adult survival (as compared to controls) of P-element lines during CH. In contrast, during IH treatment the up-regulation of Mdr49 and l(2)08717 genes (P-element lines) provided survival advantage over controls. This suggests that the increased transcript levels following treatment with either paradigm play an important role in tolerance to severe hypoxia. Furthermore, by over-expressing Hsp70 in specific tissues, we found that up-regulation of Hsp70 in heart and brain play critical role in tolerance to CH in flies. Conclusions/Significance: We observed that the gene expression response to IH or CH is specific and paradigm-dependent. We have identified several genes Hsp23, Hsp70, CG1600, l(2)08717 and Mdr49 that play an important role in hypoxia tolerance whether it is in CH or IH. These data provide further clues about the mechanisms by which IH or CH lead to cell injury and morbidity or adaptation and survival. Experiment Overall Design: Expression profiles were determined by expression arrays in Drosophila melanogaster following acute constant or intermittent hypoxia. Three groups of samples were included in this analysis (3 x control, 3x CH treated and 3 x IH treated samples).
Chips
  • Chip ID: GSM374054 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM374053 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM374052 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE16198

Experiment name 0.6% Methamphetamine feeding experiments [GSE16198]
Source GEO
Experiment description Methamphetamine can trigger dopamine releasing in human brain, now used as abuse drug. Some studies have shown that specific genes and proteins responded to, methamphetamine, but little is known about the overall "omic" response of organisms to this illicit substance. Here we demonstrate that Drosophila melanogaster has the potential to give us significant insights into evolutionarily conserved responses to methamphetamine. We performed metabolome, proteome, and transciptome profiling with Drosophila treated with methamphetamine. The proteomic profiling revealed responses associated with known physiological problems that occur with methamphetamine usage in mammals. The metabolomic result showed that the metabolite trehalose was decreased significantly after methamphetamine exposure, suggesting an oxidative stress response to this drug. Many of the differential transcribed genes, including detoxification enzymes, had the potential transcription factor-binding motif YY1 associated with their upstream regulatory regions. YY1 is known to be responsive to amphetamines in mammals. For each sample, 20 virgin male flies were used to extract the mRNA. Three replicates were produced for each treatments. Two treatments were produced (control VS 0.6% 24 h meth-fed).
Chips
  • Chip ID: GSM406534 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM406533 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM406535 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE1690

Experiment name Transcription profiling of Drosophila pooled Malpighian tubules vs. whole fly [GSE1690]
Source GEO
Experiment description This is an affymetrix array experiment comparing the transcriptome of the Malpighian tubule (or renal tubule) of 7-day adult Oregon R strain Drosophila melanogaster with matched whole fly samples. It is described in:,Wang, J., Kean, L., Yang, J., Allan, A. K., Davies, S. A., Herzyk, P. and Dow, J. A. T. (2004). Function-informed transcriptome analysis of Drosophila renal tubule. Genome Biol. In press.,There are five tubule samples (each derived from approx 1000 tubules (!)), and 5 matched whole-fly samples. i.e. tubule 2 is dissected from the same vial as WholeFly2.,As the tubule is probably the premier tissue for true physiology in Drosophila, the dataset can usefully be interrogated in conjunction with the detailed physiological understanding of the tissue: see,http://fly.to/tubules
Chips
  • Chip ID: GSM29181 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM29179 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM29180 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM29178 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM29182 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE17013

Experiment name The sexually antagonistic genes of Drosophila melanogaster [GSE17013]
Source GEO
Experiment description Differences in the selective pressures experienced by males and females are believed to be ubiquitous in dioecious organisms and are expected to result in the evolution of sexually antagonistic alleles, thereby driving the evolution of sexual dimorphism. Negative genetic correlation for fitness between the sexes has been documented, however, the identity, number and location of loci causing this relationship are unknown. Here we show that a large proportion of Drosophila melanogaster transcripts are associated with the interaction between genomic haplotype and gender and that at least 8% of loci in the fly genome are currently evolving under sexually antagonistic selection. We measured gene expression of adult males and females of Drosophila melanogaster from 15 hemiclone lines, showing either high-male/low-female fitness, high-female/lowmale fitness or average fitness in both sexes. Data from four replicates for each sex/line are presented, giving a total of 120 arrays.
Chips
  • Chip ID: GSM425584 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425634 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425594 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425539 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425533 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425531 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425580 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425607 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425631 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425562 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425572 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425537 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425559 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425582 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425565 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425643 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425627 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425604 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425600 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425620 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425534 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425591 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425602 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425550 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425575 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425642 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425568 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425563 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425557 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425605 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425617 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425630 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425544 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425609 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425564 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425530 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425615 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425543 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425547 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425561 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425581 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425611 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425546 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425560 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425621 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425606 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425583 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425574 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425589 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425598 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425625 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425552 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425529 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425612 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425541 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425554 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425610 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425596 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425644 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425535 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425569 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425577 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425588 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425571 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425645 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425542 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425595 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425622 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425551 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425614 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425566 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425636 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425640 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425613 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425639 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425592 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425629 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425624 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425548 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425590 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425540 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425608 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425567 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425585 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425536 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425578 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425532 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425616 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425545 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425555 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425647 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425603 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425556 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425626 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425538 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425576 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425635 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425599 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425623 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425587 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425628 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425619 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425570 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425586 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425549 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425553 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425618 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425637 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425646 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425593 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425597 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425558 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425579 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425632 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425528 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425641 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425573 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425633 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425601 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM425638 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE18502

Experiment name Transcription profiling of Drosophila melanogaster spermatogenesis: mitotic, meiotic and post-meiotic cells [GSE18502]
Source GEO
Experiment description We conducted a genome-wide expression analysis of wild-type males using three cell populations isolated from mitotic, meiotic and post-meiotic phases of spermatogenesis in Drosophila melanogaster. Our approach was to directly isolate testis regions enriched with RNAs from each of the three specific germline phases. We used microarrays to detail the global gene expression profile in spermatogenesis and identified up- and down-regulated genes between two different spermatogenic phases in pairwise comparisons Experiment Overall Design: Cell types present at various stages of spermatogenesis are generally located in a gradient along the proximal-distal axis of the testis, however most are not exclusively restricted to any one geographic region. Cells enriched for mitotic, meiotic and post-meiotic phases were obtained by dissection of apical, proximal and distal regions of the testis, respectively
Chips
  • Chip ID: GSM461123 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00007000
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM461121 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00007000
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM461120 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00007000
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM461119 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00007000
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM461124 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00007000
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM461125 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00007000
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM461118 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00007000
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM461122 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00007000
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE18576

Experiment name Transcription profiling of Drosophila DHR96 nuclear receptor mutants [GSE18576]
Source GEO
Experiment description DHR96 is a Drosophila member of the CAR/PXR/LXR family of Nuclear receptors. To Identify potential target genes for the DHR96 nuclear receptor we used microarray analysis to identify genes that were mis-regulated relative to control animals in the DHR96 mutant. Experiment Overall Design: Total RNA was isolated from mature adult DHR96 mutant and genetically matched Canton S controls and subjected to affymetrix microarray analysis.
Chips
  • Chip ID: GSM462145 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM462146 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM462147 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE20202

Experiment name Expression data from adult male Drosophila heads [GSE20202]
Source GEO
Experiment description A Drosophila microRNA (dme-miR-14) is involved in regulating the levels of insulin-like peptides (ilps) from the neuronal insulin-producing cells (IPCs). This is crucial for regulation of fat content in adult flies. Finding the target of this microRNA is crucial for understanding the regulation of ilp gene expression. We used microarrays to identify genes that are upregulated specifically in the neuronal IPCs in the microRNA mutants. Drosophila adult head RNA was extracted and hybridized on Affymetrix microarrays. We reared animals from early larval stages in controlled growth and feeding conditions. RNA was extracted from 5-day-old adult males. We collected RNA from control, homozygous dme-miR-14 mutants and mutants expressing dme-miR-14 microRNA specifically in the IPCs (rescue). We were interested in genes that were upregulated in the mutants and were restored or reduced to control levels in the rescue condition. Two biological replicates per sample type were performed.
Chips
  • Chip ID: GSM506739 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM506738 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE21182

Experiment name Curcumin Extends Lifespan, Improves Healthspan, and Modulates the Expression of Age-Associated Aging Genes in Drosophila melanogaster [GSE21182]
Source GEO
Experiment description Curcumin, a yellow pigment extracted from the rhizome of the plant Curcuma longa (turmeric) has been widely used as a spice and herbal medicine in Asia. It has been suggested to have many biological activities such as anti-oxidative, anti-inflammatory, anti-cancer, chemopreventive, and anti-neurodegenerative properties. We evaluated the impact of curcumin on lifespan, fecundity, feeding rate, oxidative stress, locomotion and gene expression in two different wild type Drosophila melanogaster strains, Canton-S and Ives, under two different experimental conditions. We report that curcumin extended the lifespan of two different strains of Drosophila and was accompanied by protection against oxidative stress, improvement in locomotion and chemopreventive effects. Curcumin also modulated the expression of several aging related genes (genes with age-dependent changes in gene expression) such as mth, thor, InR, and JNK. In order to evaluate the impact of curcumin and aging on gene expression, we first determined which genes were affected by aging alone in Canton S flies. Age-related changes in gene expression were defined as changes in expression levels that occurred between 3 and 40 days of age (median lifespan). Among the 18,880 probe sets in the Affymetrix GeneChip Drosophila Genome 2.0 Array, 1,383 genes (Data on file, 7.3%, P < 0.05) had statistically significant changes in expression levels during this time frame. We next determined the effect of curcumin on gene expression levels in young and aged Canton S flies. Gene expression were defined as changes in expression levels that occurred between 3 and 40 days of aged flies with or without curcumin-feeding.
Chips

Affymetrix experiment GSE22437

Experiment name mRNA expression in female Drosophila melanogaster heads at 10 days and 40 days [GSE22437]
Source GEO
Experiment description Expression data for aging female drosophila melanogaster Female drosophila heads were collected RNA extraction and hybridization on Affymetrix microarrays.
Chips
  • Chip ID: GSM557546 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM557545 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM557544 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM557543 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM557548 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM557547 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE22689

Experiment name Chromosomal Fragile Site FRA16D tumor suppressor gene Wwox contributes to aerobic metabolism and oxidative stress response [GSE22689]
Source GEO
Experiment description he WWOX gene spans chromosomal fragile site FRA16D, a region of DNA instability in cancer. While WWOX has some tumor suppressor characteristics, its normal role and functional contribution to cancer are unclear. Drosophila homozygous Wwox mutants are viable with no discernable phenotype. Drosophila Wwox interactors, identified by proteomics and micro-array analyses, mainly have roles in aerobic metabolism. Functional relationships between Wwox and either isocitrate dehydrogenase (IDH) or superoxide dismutase 1 (Sod1) were confirmed by phenotype modification, including Sod1 "crinkled-wing", indicative of oxidative stress response. Endogenous reactive oxygen species levels reflect Wwox levels in Drosophila. WWOX mRNA levels in Drosophila and human cells correlate with IDH and Sod1 levels. Wwox therefore contributes to pathways involving glucose metabolism and oxidative stress response. Drosophila embryos were harvested between 4-8hrs and total RNA isolated to look for gene-expression differences induced by the presence of one of two altered Wwox alleles relative to wild-type. The two alleles were Wwox (a null mutation generated by homologous recombination) and Wwoxf04545 carrying a pBac insertion in exon 2 (O'Keefe et al., 2005, 2007). Embryo pools were isolated in triplicate, providing 3 biological replicates.
Chips

Affymetrix experiment GSE23336

Experiment name Expression data from Drosophila melanogaster err mutant animals vs. wild type animals at a mid-second instar larval time [GSE23336]
Source GEO
Experiment description Cancer cells utilize a unique form of aerobic glycolysis, called the Warburg effect, to efficiently produce the macromolecules required for proliferation. Here we show that a metabolic program related to the Warburg effect is used during normal Drosophila development and regulated by the fly ortholog of the Estrogen-Related Receptor (ERR) family of nuclear receptors. dERR null mutants die as second instar larvae with abnormally low ATP levels, diminished triacylglyceride stores, and elevated levels of circulating sugars. Metabolomic profiling revealed that the pathways affected in these mutants correspond to those used in the Warburg effect. The expression of active dERR protein in mid-embryogenesis triggers a coordinate switch in gene expression that drives a metabolic program supporting the dramatic growth that occurs during larval development. This study suggests that mammalian ERR family members may promote cancer by directing a metabolic state that supports proliferation. Drosophila larvae were staged at a mid-second instar time point and hand sorted for developmental progression. Individual pools of isogenic animals were collected for each replicate. Three replcates were assayed for each genotype. The two genotypes assayed were a control wild type strain (w1118) and a transheteroallelic combination of err mutant alleles (err1/err2). Labled RNA was then hybridized onto Affymetrix microarrays.
Chips
  • Chip ID: GSM572698 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM572696 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM572697 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE23346

Experiment name CrebA is a major and direct regulator of secretory pathway gene expression [GSE23346]
Source GEO
Experiment description Abstract: Secretion occurs in all cells, with relatively low levels in most cells and extremely high levels in specialized secretory cells, such as those of the pancreas, salivary and mammary glands. Here, we report that the CrebA/Creb3-like family of bZip transcription factors functions to upregulate expression of both the general protein machinery required in all cells for secretion and of cell-type specific secreted proteins. Drosophila CrebA directly binds the enhancers of secretory pathway genes and is both necessary and sufficient to activate expression of every secretory pathway component gene examined thus far. Microarray profiling reveals that CrebA also upregulates expression of genes encoding cell type specific secreted components. Finally, we find that the human CrebA orthologues, Creb3L1 and Creb3L2, have the ability to upregulate the secretory pathway in non-secretory cell types. Goals: The goals of the microarray experiments were to identify additional targets of the CrebA transcription factor to learn the range of genes regulated by this transcription factor during embryogenesis. Previous work had indicated that CrebA upregulates the protein machinery of the early secretory pathway. Our new data now shows that in addition to the protein machinery, CrebA also upregulates genes encoding the protein cargo that is secreted from specialized secretory organs. RNA was isolated from stage 11-15 wild type Drosophila embryos and compared to RNA from CrebA null mutant embryos of the same age; all samples were hybridized to the Drosophila Genome 2.0 Affymetrix array. Three individual replicates were obtained for each sample.
Chips
  • Chip ID: GSM572951 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM572949 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM572950 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE23355

Experiment name Expression profile for Drosophila Sox14 at onset of metamorphosis [GSE23355]
Source GEO
Experiment description We used microarray analysis of RNA obtained from w1118 and w1118;sox14L1/sox14L1 animals staged at pupariation to identify genes regulated by Drosophila Sox14 at the onset of metamorphosis. RNA isolated from whole Drosophila w1118 and w1118; sox14L1/sox14L1 animals selected immediately after pupariation was hybridized on Affymetrix Drosophila Genome 2.0 Arrays. Each genotype was assayed independently three times with samples obtained from 10 prepupae.
Chips
  • Chip ID: GSM573178 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005342
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM573177 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005342
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM573179 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005342
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE24156

Experiment name Drosophila_2hr_mated [GSE24156]
Source GEO
Experiment description We hypothesized that social interactions, such as those involved in courtship and mating, would lead to assayable changes in gene expression that may have important effects on individual reproductive success and fitness through alterations in physiology or changes in nervous system function. Five-day-old males were collected two hours after mating with or courting a virgin female compared to males that were left alone for the 2 hrs. After collection, RNA was extracted from male head tissue. Five samples for each treatment were hybridized to Affymetrix Drosophila Genome arrays for a total of 15 arrays. Data were analyzed using dChip PM, dChip PM-MM, MAS5.0, R/Bioconductor GC-RMA, and GeneSpring GC-RMA.
Chips

Affymetrix experiment GSE24167

Experiment name Drosophila_20min_courtship [GSE24167]
Source GEO
Experiment description We hypothesized that social interactions, such as those involved in reproductive behaviors, would lead to immediate and assayable changes in gene expression that may have important effects on individual reproductive success and fitness through alterations in physiology or via short-term or long-term changes in nervous system function. Five-day-old males were exposed or mock-exposed to a virgin female fly for 20 min. Exposed males that courted, as well as mock-exposed males, were collected for RNA extraction of head tissue. Five samples for each treatment were hybridized to Affymetrix Drosophila Genome arrays for a total of 15 arrays. Data were analyzed using dChip PM, dChip PM-MM, MAS5.0, R/Bioconductor GC-RMA, and GeneSpring GC-RMA.
Chips

Affymetrix experiment GSE2422

Experiment name Transcription profiling of Drosophila wild type vs TIM-MJD mutants after LD growth [GSE2422]
Source GEO
Experiment description WT flies or flies of the strain Tim-gal4; UAS-MJD78Q. All samples were collected at ZT16 after 3 days of training in LD conditions.
Chips
  • Chip ID: GSM45592 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM45593 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE25522

Experiment name Larval host gene expression study in Drosophila post parasitic wasp-infection [GSE25522]
Source GEO
Experiment description Upon pathogenic infection, drosophila larval host mounts an immune response. Parasitic wasps inject venom that contain virulence factors during oviposition, which can elicit host immune response, and in some cases, suppress host immune responses altogether. Several microarray experiments have been performed on different classes of parasitic wasps. We wanted to compare how Ganaspis xanthopoda-infected hosts respond compared to other classes of parasitic wasps. Third instar y w larvae from a 2-day egglay were infected with G. xanthopoda for three and six hours, respectively, by introducing waps in petri-dish containing larvae. Controls were handled side-by-side without introducing wasps. Host larvae were immediately dissected, infection confirmed by presence of wasp egg, and frozen in liquid nitrogen and ground in Trizol. RNA was isolated and checked by agarose gel-electrophoresis. Samples were then sent to the Microarray Core Facility at Weill Cornell Medical College.
Chips
  • Chip ID: GSM627505 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM627503 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE25988

Experiment name Expression data from Drosophila dLmo (EP1306 and BxJ) mutants [GSE25988]
Source GEO
Experiment description The Drosophila gene dLmo encodes a transcriptional regulator involved in wing development and behavioral responses to cocaine and ethanol. We were interested in discovering novel transcriptional targets of dLmo in the nervous system by examining gene expression changes in the heads of wild-type flies and flies carrying dLmo loss-of-function (EP1306) and gain-of-function mutants (BxJ). RNA was isolated from 3 pooled groups of 200 fly heads from each genotype (w;iso control, EP1306, and BxJ) and hybridized to triplicate Affymetrix Drosophila 2.0 oligonucleotide microarray chips at the Partners HealthCare Center for Personalized Genetic Medicine microarray facility (Harvard University).
Chips
  • Chip ID: GSM637982 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM637983 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM637981 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE26724

Experiment name Transcription profiling by array of female Drosophila after feeding resveratrol [GSE26724]
Source ArrayExpress
Experiment description Feeding resveratrol to Drosophila melanogaster extends lifespan. Studies of microarray show similarities between calorie/dietary restriction and resveratrol on both a gene expression and biological pathway level. 9 samples: 3 biological replicates each of normal diet, restricted diet and normal diet plus resveratrol
Chips
  • Chip ID: GSM658003 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000002 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM658002 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000002 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM658001 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000002 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE26726

Experiment name Expression Data From Dietary Restriction, p53 Knockdown and sir2 Overexpression Mutants [GSE26726]
Source GEO
Experiment description Expression data from four different lifespan-extending conditions: dietary restriction in two different genetic backgrounds (canton-s and a yw, w1118 combination), sir2 overexpression and p53 knockdown (+/-). Comparison of significantly over and under-expressed genes reveals a signature for dietary restriction and lifespan extension. Abstract A major challenge in translating the positive effects of dietary restriction (DR) for the improvement of human health is the development of therapeutic mimics. One approach to finding DR mimics is based upon identification of the proximal effectors of DR life span extension. Whole genome profiling of DR in Drosophila shows a large number of changes in gene expression, making it difficult to establish which changes are involved in life span determination as opposed to other unrelated physiological changes. We used comparative whole genome expression profiling to discover genes whose change in expression is shared between DR and two molecular genetic life span extending interventions related to DR, increased dSir2 and decreased Dmp53 activity. We find twenty-one genes shared among the three related life span extending interventions. One of these genes, takeout, thought to be involved in circadian rhythms, feeding behavior and juvenile hormone binding is also increased in four other life span extending conditions: Rpd3, Indy, chico and methuselah. We demonstrate takeout is involved in longevity determination by specifically increasing adult takeout expression and extending life span. These studies demonstrate the power of comparative whole genome transcriptional profiling for identifying specific downstream elements of the DR life span extending pathway. 42 samples were used in the analysis. Sir2 overexpression flies and the yw, w1118 background DR flies had the same control. Flies were collected at ages 10 and 40 days. Tissue is whole body females.
Chips
  • Chip ID: GSM658066 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM658067 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM658060 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM658062 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM658068 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM658061 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE27076

Experiment name Female Drosophila melanogaster gene expression and mate choice: candidate genes underlying sexual isolation [GSE27076]
Source GEO
Experiment description Background The evolution of female choice mechanisms favouring males of their own kind is considered as crucial step during the early stages of speciation. However, although the genomics of mate choice may influence both the likelihood and speed of speciation, the identity and location of genes underlying assortative mating remain largely unknown. Methods and Findings We used mate choice experiments and gene expression analysis of female D. melanogaster to examine three key components influencing speciation. We show that the 1,498 genes in Zimbabwean female Drosophila melanogaster whose expression levels differ when mating with more (Zimbabwean) versus less (Cosmopolitan strain) preferred males include many with high expression in the central nervous system and ovaries, are disproportionately X-linked and form a number of clusters with low recombination distance. Significant involvement of the brain and ovaries is consistent with the action of a combination of pre- and postcopulatory female choice mechanisms, while sex linkage and clustering of genes lead to high potential evolutionary rate and sheltering against the homogenizing effects of gene exchange between populations. Conclusion Taken together our results imply favourable genomic conditions for the evolution of reproductive isolation through mate choice in Zimbabwean D. melanogaster and suggest that mate choice may, in general, act as an even more important engine of speciation than previously realized. We measured gene expression of adult female Drosophila melanogaster from a composite Zimbabwe (Z) strain population named SZ, produced by mixing the genomes of six Z strain isofemale lines, shortly after mating them with either SZ strain or cosmopolitan (M strain) males. Data from four replicates of each of the two treatments (SZ mated with SZ; SZ mated with M) are presented, giving a total of eight arrays.
Chips

Affymetrix experiment GSE27927

Experiment name Transcription profiling by array of Drosophila after fasting [GSE27927]
Source ArrayExpress
Experiment description The sensation of hunger after a period of fasting and the sensation of satiety after eating is crucial to behavioral regulation of food intake, but the biological mechanisms regulating these sensations are incompletely understood. We studied the behavioral and physiological adaptation to fasting in the vinegar fly (Drosophila melanogaster). Here we show that flies demonstrated increased behavioral attraction to food odor when food-deprived with no corresponding increase in sensitivity in the peripheral olfactory system. Flies increased their food intake transiently in the post-fasted state, but returned to a stable baseline feeding level within 24 hr after return to food. This modulation in feeding was accompanied by a significant increase in the size of the crop organ of the digestive system, suggesting that fasted flies responded both by increasing their food intake and storing reserve food in their crop. The post-fasting feeding response was observed in both male and female flies of diverse genetic backgrounds. Expression profiling of head, body, and chemosensory tissues by microarray analysis revealed several hundred genes that are regulated by feeding state, including 247 genes in the fly head. We performed RNA interference-mediated knockdown of, takeout, one of the genes strongly downregulated by fasting in multiple tissues. When takeout was knocked down in all neurons the post-fasting feeding response was abolished. These observations suggest that a coordinated transcriptional response to internal physiological state may regulate both ingestive behaviors and chemosensory perception of food 6 Pool of flies were used for this experiment. For each pool, samples were taken at 0,24 and 48h and separated in each body part. 56 samples were used for the analysis.
Chips
  • Chip ID: GSM690633_1_A0-4_Drosophila_2.0_Shelli_080708 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004511 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690685_12_B0-8_Drosophila_2.0_Shelli_092408 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000002 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690643_39_A0-8_Drosophila_2.0_Shelli_082608 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004511 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690674_44_P0-9_Drosophila_2.0_Shelli_082608 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004540 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690688_15_B0-9_Drosophila_2.0_Shelli_092408 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000002 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690657_40_H0-8_Drosophila_2.0_Shelli_082608 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690650_11_H0-5_Drosophila_2.0_Shelli_080708 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690660_43_H0-9_Drosophila_2.0_Shelli_082608 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690666_38_P0-6_Drosophila_2.0_Shelli_082608 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004540 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690661_3_P0-4_Drosophila_2.0_Shelli_080708 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004540 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690646_42_A0-9_Drosophila_2.0_Shelli_082608 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004511 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690671_41_P0-8_Drosophila_2.0_Shelli_082608 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004540 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690675_1_B0-4_Drosophila_2.0_Shelli_092408 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000002 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690652_37_H0-6_Drosophila_2.0_Shelli_082608 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690647_2_H0-4_Drosophila_2.0_Shelli_080708 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690664_12_P0-5_Drosophila_2.0_Shelli_080708 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004540 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690636_10_A0-5_Drosophila_2.0_Shelli_080708 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004511 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690678_4_B0-5_Drosophila_2.0_Shelli_092408 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000002 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM690680_7_B0-6_Drosophila_2.0_Shelli_092408 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000002 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE2828

Experiment name Transcription profiling of Drosophila infected with Drosophila C virus reveals a third evolutionary conserved innate immunity pathway operates in drosophila and counters viral infection [GSE2828]
Source GEO
Experiment description The response of drosophila to bacterial and fungal infections involves two signaling pathways, Toll and Imd, which both activate NF-kB family members. We have studied the global transcriptional response of flies to infection with drosophila C virus. Viral infection induced a set of genes distinct from those regulated by the Toll or Imd pathways, and triggered activation of a STAT binding activity. Genetic experiments showed that the JAK kinase Hopscotch was involved in the control of the viral load in infected flies, and was required, though not sufficient, for the induction of some virus-regulated genes. Our results indicate that in addition to Toll and Imd, a third evolutionary conserved innate immunity pathway operates in drosophila and counters viral infection.
Chips
  • Chip ID: GSM61890 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM61886 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM61892 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM61888 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM61891 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM61889 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE29815

Experiment name Transcription profiling by array of Drosophila ovarian follicles mutant for pxt [GSE29815]
Source ArrayExpress
Experiment description Gene expression analysis of yw follicles at S9/10a, S10B, S12, and S14; Gene expression analysis of pxt mutant follicles (f01000 and EY03052) at S10B, S12, S14 Drosophila ovarian follicles complete development using a spatially and temporally controlled maturation process in which they resume meiosis and secrete a multi-layered, protective eggshell before undergoing arrest and/or ovulation. Microarray analysis revealed more than 150 genes that are expressed in a stage-specific manner during the last 24 hours of follicle development. These include all 30 previously known eggshell genes, as well as 19 new candidate chorion genes and 100 other genes likely to participate in maturation. Mutations in pxt, encoding a putative Drosophila cyclooxygenase, cause many transcripts to begin expression prematurely, and are associated with eggshell defects. Somatic activity of Pxt is required, as RNAi knockdown of pxt in the follicle cells recapitulates both the temporal expression and eggshell defects. One of the temporally regulated genes, cyp18a1, which encodes a cytochromome P450 protein mediating ecdysone turnover, is downregulated in pxt mutant follicles, and cyp18a1 mutation itself alters eggshell gene expression. These studies further define the molecular program of Drosophila follicle maturation and support the idea that it is coordinated by lipid and steroid hormonal signals. minimum of 2 replicates per stage and genotype. yw=control follicles. pxt=mutant follicles.
Chips
  • Chip ID: GSM738894 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005272 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM738893 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005272 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM738896 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005272 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM738892 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004886 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM738891 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004886 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE30020

Experiment name Transcription profiling by array of Drosophila Canton-S larvae fed high-sugar diet [GSE30020]
Source ArrayExpress
Experiment description Chronic high sugar feeding induces obesity, hyperglycemia, and insulin resistance in flies and mammals. To gain insight into the mechanisms underlying this response, we profiled gene expression in chronically high sugar fed, wandering (post-prandial) third instar wild type larvae (L3). These data were compared to control-fed larvae as well as those (mid-L3) actively feeding for twelve hours on both diets. We used microarrays to detail the response of Drosophila larvae to high sugar-induced insulin resistance. Male Canton-S third instar larvae were fed control (0.15M) or high (1M) sucrose and selected for RNA extraction and hybridization on Affymetrix microarrays. Wandering L3 were selected as those in the top half of the vial with partial blue guts to confirm that they had stopped eating the (blue) food. Mid-L3 were selected as L2, aged overnight until early L3, then transferred to fresh control or high sucrose food for 12 more hours before selection.
Chips
  • Chip ID: GSM742989 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005341
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM742990 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005341
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM742991 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005341
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE33989

Experiment name Expression data from third instar Drosophila larvae offspring from maternal control or high-sucrose fed diets [GSE33989]
Source ArrayExpress
Experiment description Maternal obesity and diabetes is associated with increased risk of obesity and diabetes in offspring. We generated a model of maternal caloric excess in Drosophila and noted altered body composition in offspring from females fed a high-sucrose diet. To gain insight into the mechanisms underlying this response, we profiled gene expression in mid-third instar larvae (mid-L3) offspring from either control or high-sucrose fed females. All offspring were raised on control food. We used microarrays to detail the response of Drosophila larvae to maternal high calorie diet Virgin female w1118 flies were fed control (0.15M) or high (1M) sucrose food for 7 days, mated with male w1118 flies such that all embryos were laid on control food. Mid-L3 larvae were selected for RNA extraction and hybridization on Affymetrix microarrays. Mid-L3 were selected as L2, aged overnight until early L3, then transferred to fresh control food for 12 more hours before selection.
Chips
  • Chip ID: GSM840105_18727 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005339 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM840107_18729 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005339 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM840106_18728 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00005339 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE3842

Experiment name Transcription profiling of Drosophila LD/DD time course of y w; tim01, cn bw, and y w [GSE3842]
Source GEO
Experiment description This SuperSeries is composed of the following subset Series:; GSE3826: LD/DD time course of y w Drosophila #1; GSE3828: LD/DD time course of y w Drosophila #2; GSE3829: LD/DD time course of cn bw Drosophila; GSE3830: LD/DD time course of y w Drosophila #3; GSE3831: LD/DD time course of y w; tim01 Drosophila #1; GSE3832: LD/DD time course of y w; tim01 Drosophila #2 Experiment Overall Design: Refer to individual Series
Chips
  • Chip ID: GSM80127 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80142 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80129 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80121 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80134 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80132 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80128 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80139 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80133 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80137 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80119 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80124 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80116 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80151 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80135 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80111 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80136 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80112 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80152 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80141 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80148 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80105 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80143 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80122 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80123 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80110 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80144 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80113 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80130 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80126 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80146 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80147 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80120 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80149 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80118 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80107 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80117 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80150 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80138 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80109 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80114 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80145 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80108 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80115 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80106 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM80140 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE4174

Experiment name Transcription profiling of whole Drosophila brains fron animals exposed to sleep deprivation [GSE4174]
Source GEO
Experiment description Analysis of brain of Canton-S females deprived of sleep by perturbations during their normal sleep period. Perturbation effect also assessed during their active period to control for its effect during sleep deprivation. Results suggest processes altered during prolonged wakefulness and during sleep.
Chips
  • Chip ID: GSM95424 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM95444 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM95292 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM95293 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM95425 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE4188

Experiment name Transcription profiling of whole testis from wild type, bgcn- and Os+bgcn- Drosophila [GSE4188]
Source GEO
Experiment description Whole testes were dissected from adult males. RNA from five or six biological replicates were generated and the expression profiles were determined using Affymetrix Drosophila Genechip 1 arrays. Comparisons between the bgcn- and Os+bgcn- groups allowed for the identification of stem cell genes.
Chips
  • Chip ID: GSM95945 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM95946 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM95943 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM95942 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM95944 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE4789

Experiment name Transcription profiling of Drosophila to investigate pleiotropic fitness effects of the Tre1/Gr5a region [GSE4789]
Source GEO
Experiment description The abundance of transposable elements and DNA repeat sequences in mammalian genomes raises the question whether such insertions represent passive evolutionary baggage or may influence the expression of complex traits. We addressed this question in Drosophila melanogaster where the effects of single transposable elements on complex traits can be assessed in genetically identical individuals reared in controlled environments. Here we demonstrate that single P-element insertions in the intergenic region between the Gustatory receptor 5a (Gr5a) and Trapped in endoderm 1 (Tre1), which encodes an orphan receptor, exert complex pleiotropic effects on fitness traits, including selective nutrient intake, resistance to starvation and heat stress, and life span. Mutations in this region interact epistatically with downstream components of the insulin signaling pathway. Transposon-induced sex-specific and sex-antagonistic effects further accentuate the complex influences intergenic transposable elements can contribute to complex phenotypes. SUBMITTER_CITATION: Rollmann SM, Magwire MM, Morgan TJ, Ozsoy ED, Yamamoto A, Mackay TF, Anholt RR. Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster. Nat Genet. 2006 Jul;38(7):824-9. Experiment Overall Design: BG02514, BG02257 and Canton S (B) lines were reared simultaneously at 25 C under a 12 h light/dark cycle and 70% humidity. At 5-7 days post-eclosion, we removed the heads of two replicate groups of 100 males and 100 females for each line. Total RNA was isolated from each replicate and biotinylated cRNA probes were hybridized to high density oligonucleotide microarrays (Affymetrix, Inc.) and visualized with a streptavidin-phycoerythrin conjugate, as described in the Affymetrix GeneChip Expression Analysis Technical Manual (2000), using internal references for quantification. The quantitative estimate of expression of each probe set is the Signal (Sig) metric, as described in the Affymetrix Microarray Suite, Version 5.0. Sig values were analyzed by two-way ANOVA according to the model Y = + L + S + LxS + E, where L is the effect of line, S is the effect of sex and E the error variance
Chips
  • Chip ID: GSM108179 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM108177 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM108178 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM108176 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality

Affymetrix experiment GSE5012

Experiment name Transcription profiling of Drosophila mated females to identify mating response genes [GSE5012]
Source GEO
Experiment description Male-derived accessory gland proteins (Acps) that are transferred to females during mating have profound effects on female reproductive physiology including increased ovulation, mating inhibition, and effects on sperm utilization and storage. The extreme rates of evolution seen in Acps may be driven by sperm competition and sexual conflict, processes which may ultimately drive complex interactions between female- and male-derived molecules and sperm. However, little is known of how gene expression in female reproductive tissues changes in response to the presence of male molecules and sperm. To characterize this response, we conducted parallel genomic and proteomic analyses of gene expression in the reproductive tract of 3-day-old unmated and mated female Drosophila melanogaster. Using DNA microarrays, we identified 539 transcripts that are differentially expressed in unmated vs. mated females and revealed a striking peak in differential expression at 6 hrs postmating and a marked shift from primarily down-regulated to primarily up-regulated transcripts within 3 hrs after mating. Combining two-dimensional gel electrophoresis and liquid chromatography mass spectrometry analyses, we identified 84 differentially expressed proteins at 3 hrs postmating, including proteins which appeared to undergo post-translational modification. Together, our observations define transcriptional and translational response to mating within the female reproductive tract and suggest a bimodal model of postmating gene expression initially correlated with mating and the final stages of female reproductive tract maturation and later with the declining presence of male reproductive molecules and with sperm maintenance and utilization. Experiment Overall Design: Three-day-old mated and unmated females were dissected to remove the lower reproductive tract (upper uterus, sperm-storage organs, and accessory glands). Mated females were dissected either immediately following mating (0 hr) or at 3, 6, or 24 hrs following the termination of mating. Tracts of 12-40 females of like category were pooled and total RNA extracted via a TRIzol-based protocol. Processing and labeling of transcript was performed by the Molecular Biology Core Facility at the Medical College of Georgia. Arrays from mated females at the different timepoints were compared to unmated females.
Chips
  • Chip ID: GSM112943 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112962 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112965 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112935 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112971 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112948 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: low quality
  • Chip ID: GSM113345 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112942 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112963 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112947 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112972 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112950 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: low quality
  • Chip ID: GSM112968 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: low quality
  • Chip ID: GSM112945 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112952 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112970 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM112931 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112967 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112964 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: low quality
  • Chip ID: GSM112946 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality
  • Chip ID: GSM112949 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004864 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: low quality

Affymetrix experiment GSE5404

Experiment name Transcription profiling of Drosophila selected for aggressive behavior over 28 generations vs controls [GSE5404]
Source GEO
Experiment description Genes relevant to manifestion of and variation in aggression behavior might be differentially expressed in lines selected for divergent levels of aggression. Experiment Overall Design: Drosophila males were assessed for their aggression levels in a behavioral assay that quantified aggressive encounters. A subset of the sampled population was selected as parents for the next generation, with High, Low, and Control selection groups maintained. This artificial selection was continued for 28 generations, with a variety of other behavioral and life history traits assessed for correlation with response to selection for aggression. At generation 28, male and female flies were collected for RNA extraction and subsequent gene expression analysis.
Chips
  • Chip ID: GSM123492 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123498 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123506 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123495 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123512 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123511 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123501 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123513 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123491 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123508 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123497 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123499 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123509 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123510 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123490 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123500 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123493 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM123502 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM123505 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123503 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM123494 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123504 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123507 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM123496 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE6490

Experiment name Transcription profiling of Drosophila CA/AA time course of y w [GSE6490]
Source GEO
Experiment description Circadian clocks are temporally aligned to the environment via signals, or Zeitgebers, such as daily light and temperature cycles, food availability, and social behavior. In this study, we show that genome-wide expression profiles from temperature-entrained flies show a dramatic difference in the presence or absence of a thermocycle. Whereas transcription appears to be modified globally by changes in temperature, there is a specific set of transcripts that continue to oscillate in constant conditions following temperature entrainment. These transcripts show a significant overlap with a previously defined set of transcripts oscillating in response to a photocycle. Further, these overlapping transcripts maintain the same mutual phase relationships after entrainment by temperature or light. Comparison of the collective temperature- and light-entrained circadian phases indicates that natural environmental light and temperature cycles cooperatively entrain the circadian clock. These findings suggest that a single transcriptional clock in the adult fly head is able to integrate information from both light and temperature. Experiment Overall Design: y w flies that had been reared in constant darkness initially at 25 C and later in a 12-hr 18 C/ 12-hr 25 C thermocycle for more than 4 days were harvested every four hours during an additional 18 C/25 C thermo cycle (also indicated as a cold/ambient or CA cycle) or an additional day at constant 25 C (also indicated as ambient/ambient or AA) . Relative to time CA0 as the time of the onset of the 18 C cryophase or AA0 as the time of the onset of the subjective cryophase during constant 25 C, samples were collected in a CA2- CA6-CA10-CA14-CA18-CA22 and AA2-AA6-AA10-AA14-AA18-AA22 schedule. Heads were isolated by breaking up frozen flies and passing them through a set of sieves. RNA was prepared using guanidine-thiocyanate extraction followed by purification over a CsCl gradient. Additional purification of the RNA samples was achieved by applying them to Rneasy columns (Qiagen). Biotin-labeled cRNA probe was generated from 25 g of purified RNA and hybridized as described previously (Wijnen H, Naef F, and Young MW, Methods Enzymol. 2005; 393: 341-365). Experiment Overall Design: For more information see also http://biorhythm.rockefeller.edu
Chips
  • Chip ID: GSM148588 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM148587 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM148586 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM148585 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM148589 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE6558

Experiment name Transcription profiling of Drosophila melanogaster adult females seleected for resistance toi environmental stressors [GSE6558]
Source GEO
Experiment description A study evaluating the effect of stress resistance selection of Drosophila melanogaster. Abstract; Here, we report a detailed analysis of changes in gene expression in Drosophila melanogaster selected for multiple eological relevant environmental stress resistance traits. We analyzed females from three biological replicates from seven selection regimes and one control regime using whole genome gene expression arrays. Replicated selection lines were selected for resistance to acute heat survival, high temperature knock down, constant 30 C during development, cold shock survival, desiccation and starvation, respectively. Additionally, a set of replicated lines was selected for increased longevity. When compared to gene expression profiles of control lines, we were able to detect consistent selection responses at the transcript level in each specific selection regime and also found a group of differentially expressed genes that were generally changed among all selected lines. Replicated selection lines clustered together, i.e. showed similar changes in gene expression (compared to controls) and thus showed that 10 generations of artificial selection gives a clear signal among gene expression profiles. The changes in gene expression in lines selected for increased longevity, desiccation and starvation resistance, respectively, showed high similarities. Cold resistance selected lines showed little differentiation from controls. Different methods of heat selection (heat survival, heat knock down and constant 30 C) showed little similarity verifying that different mechanism are involved in high temperature adaptation. The direction of change in gene expression in the selected lines showed a consistent pattern for each selection regime. For most selection regimes and in the comparison of all selected lines and controls exclusively up- or down regulation of gene expression among significant differentially expressed genes was found. The different responses to selection expressed in individual selection regimes and among all selected lines indicate that we have identified genes involved in stress specific and general stress response mechanisms. Experiment Overall Design: gene expression was measured in biological triplicates of control flies and flies selected for resistance to various stressors.
Chips
  • Chip ID: GSM151708 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM151709 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM151707 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE6655

Experiment name Transcription profiling of Drosophila courtship-exposed male flies [GSE6655]
Source GEO
Experiment description I hypothesized that social interactions, such as those involved in reproductive behaviors, would lead to immediate and assayable changes in gene expression that may have important effects on individual reproductive success and fitness through alterations in physiology or via short-term or long-term changes in nervous system function. Experiment Overall Design: Four-day males were exposed or mock-exposed to a virgin female fly for 5 min. Exposed males that courted as well as mock-exposed males were collected for RNA extraction. Three samples for each treatment were hybridized to Affymetrix Drosophila Genome arrays for a total of 6 arrays.
Chips
  • Chip ID: GSM154110 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM154106 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM154105 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM154108 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM154103 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM154109 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE6839

Experiment name Transcription profiling of Drosophila Pof D119 mutant and wild type first instar larvae [GSE6839]
Source GEO
Experiment description Analysis of gene expression in pof deletion mutants. Chromosome 4 genes are down-regulated in pof mutants compared to wildtype control. 200 Drosophila melanogaster first instar larvae were used for each of three biological replicates of y1 w67c23; PofD119/PofD119 and three biological replicates of y1 w67c23 as controls. Experiment Overall Design: 200 1st instar larvae were used for each of 3 biological replicates of pof mutants and 3 replicates of wt larvae.
Chips
  • Chip ID: GSM157735 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00001727 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM157732 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00001727 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM157734 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00001727 - Developmental stage ID: FBdv:00005337
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE7614

Experiment name Transcription profiling of Drosophila artificially selected for alcohol sensitivity, highly sensitive or resistant flies vs. unselected control lines [GSE7614]
Source GEO
Experiment description Alcoholism is a complex disorder determined by interactions between genetic and environmental risk factors. Drosophila represents a powerful model system to dissect the genetic architecture of alcohol sensitivity, as large numbers of flies can readily be reared in defined genetic backgrounds and under controlled environmental conditions. Furthermore, flies exposed to ethanol undergo physiological and behavioral changes that resemble human alcohol intoxication, including loss of postural control, sedation, and development of tolerance. We performed artificial selection for alcohol sensitivity for 25 generations and created duplicate selection lines that are either highly sensitive or resistant to ethanol exposure along with unselected control lines. We used whole genome expression analysis to identify 1,678 probe sets with different expression levels between the divergent lines, pooled across replicates, at a false discovery rate of q < 0.001. We assessed to what extent genes with altered transcriptional regulation might be causally associated with ethanol sensitivity by measuring alcohol sensitivity of 37 co-isogenic P-element insertional mutations in 35 candidate genes, and found that 32 of these mutants differed in sensitivity to ethanol exposure from their co-isogenic controls. Furthermore, 23 of these novel genes have human orthologues. Combining whole genome expression profiling with selection for genetically divergent lines is an effective approach for identifying candidate genes that affect complex traits, such as alcohol sensitivity. Because of evolutionary conservation of function, it is likely that human orthologues of genes affecting alcohol sensitivity in Drosophila may contribute to alcohol-associated phenotypes in humans. Experiment Overall Design: Starting with flies from Raleigh natural population (see material and methods) we performed artificial selection for alcohol sensitivity for 35 generation. In each generations we scored 60 males and females, separately, from each line (resistant, sensitive, and control)using inebriometer, and the 20 highest-scoring flies from the resistant lines and the 20 lowest-scoring flies from the sensitive lines were selected as parents for the next generation. Control line flies were scored each generation and 20 random flies were used as parents. Experiment Overall Design: At generation 25, two replicates of 15 three-five day old virgin males and females were collected from each selection line. Total RNA was extracted from the 24 samples . Biotinylated cRNA probes were hybridized to high density oligonucleotide microarrays (Affymetrix, Inc. Drosophila GeneChip 2.0) and visualized with a streptavidin-phycoerythrin conjugate, as described in the Affymetrix GeneChip Expression Analysis Technical Manual (2000), using internal references for quantification. The quantitative estimate of expression of each probe set is the Signal (Sig) metric, as described in the Affymetrix Microarray Suite, Version 5.0.
Chips
  • Chip ID: GSM183815 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM183993 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM183816 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM183856 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM183992 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM183990 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM183991 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM183817 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE7763

Experiment name Transcription profing of Drosophila tissues in adult and larva [GSE7763]
Source GEO
Experiment description A new online resource (flyatlas.org) provides the most comprehensive view yet of expression in multiple tissues of Drosophila. Meta-analysis of the data reveals that a significant fraction ofthe genome is expressed with great tissue specificity in the adult, demonstrating the need for the functional genomic community to embrace a wider range of functional phenotypes. Well-known developmental genes are often re-used in surprising tissues in the adult, suggesting new functions. The homologues of many human genetic disease loci show selective expression in Drosophila tissues with function analogous to the affected tissues in the cognate human disease, providing a useful filter for potential candidate genes. Experiment Overall Design: FlyAtlas is composed of data covering 8 distinct adult tissues (brain, head, midgut, Malpighian tubules,hindgut, testis, ovary, male accessory glands) so far, together with two larval tissues (tubule, fat body), each run with 4 replicates on Affymetrix Dros Genome 2 chips (with probesets for 18770 transcripts), and compared with a matched whole-fly sample.
Chips
  • Chip ID: GSM188097 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004482 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188115 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188108 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM188112 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188103 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00001896 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188101 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00001896 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188106 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004865 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188083 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM188086 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188072 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003143 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188098 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004482 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188085 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188102 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00001896 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM188089 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188091 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188110 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM188096 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004482 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188078 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003138 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188104 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004865 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188100 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00001896 - Developmental stage ID: FBdv:00005339
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188088 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188090 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188081 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM188079 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003138 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM188114 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188080 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM188077 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003138 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188084 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188075 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003143 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188099 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004482 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188107 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004865 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188113 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188105 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004865 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM188109 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188082 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM188087 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003624 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188111 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM188076 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003138 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188074 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003143 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM188073 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003143 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE7772

Experiment name Transcription profiling of mouse how germ-line clones embryos and WT embryos at 3-5 h AEL [GSE7772]
Source GEO
Experiment description Mutant embryos lacking maternal and zygotic HOW exhibit defects in mesoderm development. How is an RNA binding protein that regulates the levels of mRNAs by controling RNA metabolism. To gain an insight as to the profile of mRNAs regulated by HOW during early mesoderm development we analyzed the array of mRNAs whose levels are altered in the how mutant embryos. Experiment Overall Design: Embryos lacking both maternal and zygoic HOW were selected using a GFP balancer. The mRNA of 5 collections of 3-5 hrs old WT or how mutant embryos were pooled and used for each microarray experiment. Two microarray experiments were performed from independent samples.
Chips
  • Chip ID: GSM188344 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM188346 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE7873

Experiment name Transcription profiling of males from Drosophila simulans, Drosophila mauritiana, Drosophila melanogaster, Drosophila santomea, Drosophila sechellia, Drosophila teissieri, Drosophila yakuba [GSE7873]
Source GEO
Experiment description Co-expression of genes that physically cluster together is a common characteristic of eukaryotic transcriptomes. Identifying these groups of co-expressed genes is important to the functional annotation of genomes and understanding the evolutionary fates of the clustered genes. We used microarrays to measure gene expression in seven closely related Drosophila species, to identify domains clusters within a species of Drosophila (D. simulans) and that are evolving among species in the D. melanogater subgroup. Experiment Overall Design: Assays were carried out on three independent (biological) replicates per species for a single line of the following five species: D.yakuba (Tuscon Stock Center Number: 14021-0261.00), D.santomea (TSCN: 14021-0271.00), D.teissieri (TSCN: 14021-0257.00), D.mauritiana (David 105, TSCN: 14021-0241.01), D.sechellia (Roberstson, TSCN: 14021-0248.21). Three biological replicates for D.melanogaster. The samples assayed for D.melanogaster reflect an even genotypic contribution of 10 isogenic lines developed from a wild population (Winters, CA) and crossed in a round-robin design.For D. simulans, three replicate arrays were used to assay each of 10 round-robin crosses between 10 isogenic lines developed from the same population. the entire data set therefore included a total of 48 independent transcript assays covering seven Drosophila species in the D.melanogaster subgroup
Chips
  • Chip ID: GSM190917 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM190918 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM190916 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003004 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE826

Experiment name Transcription profiling of Drosophila heads heads from adult males, w118 strain [GSE826]
Source GEO
Experiment description The w1118 strain is an inbred lab stock widely used in genetic and transgenic studies. w1118 males have a median life span of 35 days. Adult males were collected within 24 hr after eclosion. Approximately 200 flies were maintained in constant darkness in each food bottle at 25 C and 70% humidity and were transferred to fresh bottles every 3-4 days. Transcripts were harvested at d3 and d47. To separate the head from the rest of the body, flies were frozen and briefly vortexed in liquid nitrogen. Fly heads were collected using a sieve which retained fly bodies. Total RNA was extracted using Trizol (GIBCO/BRL). Poly(A) RNA was isolated using Oligotex resin (Qiagen). Samples were profiled with Affymetrix DrosGenome1 GeneChips, using standard Affymetrix protocol.
Chips
  • Chip ID: GSM12772 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: low quality
  • Chip ID: GSM12770 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: low quality

Affymetrix experiment GSE8330

Experiment name Transcription profiling of Drosophila Canton-S (wild type) and Shu mutant females treated with 50mM LiCl vs no compound to identify genes involved in the lithium-responsive neurological pathway [GSE8330]
Source GEO
Experiment description Lithium has been used for more than 50 years as the primary therapy for bipolar affective disorder (BPD) and is highly effective in its treatment. However, the molecular and cellular mechanisms underlying the lithium s therapeutic action still remains elusive. The goal of the proposed study is to identify genes involved in the lithium-responsive neurological pathway using the fruit fly as a model organism. Based on the fact that the fundamental molecular and cellular mechanisms are well conserved between the fruit fly and vertebrates, the outcomes of this project are expected to lead to the recognition of uncharacterized players or processes responsible for the lithium action in the vertebrates, which would open up the future possibility to develop novel and improved therapies for BPD. The proposed gene-profiling experiment is designed to identify candidate genes and genetic pathways involved in the lithium-responsive biological process. Specific aims of this project are; 1) identify genes whose expression levels are significantly different between the wild type and Shu, 2) identify genes whose expression levels are enhanced or suppressed after lithium treatment, and 3) identify genes whose expression is differentially regulated in the wild type and Shu after lithium treatment. We expect that the genes identified through the proposed microarray analysis will provide important clues for elucidating the molecular and cellular processes responsible for the lithium action. A Drosophila mutant Shudderer (Shu) exhibits various neurological phenotypes, including hyperactivity, uncoordinated movements, and sporadically occurring jerks. Interestingly, many of these phenotypes are greatly suppressed by lithium with the internal concentrations used for treatment of human BPD patients. In addition, Shu mutant is more resistant to the toxic effects of lithium than the wild type strain. These data have led us to the hypothesis that the biological process responsive to lithium is affected in the Shu mutant. We expect that we will be able to identify genes and genetic pathways involved in the lithium-responsive process by comparing the gene expression profiles between the wild type and the Shu mutant with or without lithium treatment. Newly eclosed Canton-S (wild type) and Shu mutant females will be placed in vials containing fly food with or without 50mM LiCl. They will be cultured at 25oC with 65% humidity for 5 days. Three groups of fifty flies (150 flies in total) will be collected for each experimental condition (i.e., genotype and lithium treatment) and frozen on dry ice. The head will be separated and total RNA will be extracted from each group using the TRIzol Reagent (Life Technologies) followed by an RNeasy (Qiagen) cleanup step and a DNase I digestion step. The RNA will be resuspended in DEPC-treated water and the absorbance will be checked at 260 and 280 nm for determination of sample purity and concentration. The GeneChip Drosophila Genome 2.0 Arrays will be used to quantify the levels of transcripts in each sample. The total number of samples will be 4 (2 genotypes and 2 treatments) X 3 (triplicate) = 12.
Chips
  • Chip ID: GSM206417 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM206419 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM206418 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00003007 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE8775

Experiment name Transcription profiling of Drosophila to investigate mutations increasing life span [GSE8775]
Source GEO
Experiment description ABSTRACT; MAGWIRE, MICHAEL MAHLON. Mutations Increasing Drosophila melanogaster; Life Span. (Under the direction of Trudy F. C. Mackay.); Better living conditions and advances in medicine have made it possible for; humans to live considerably longer than before. This has uncovered many; health problems associated with age. By identifying genes involved in the; limitation of life span, we may better understand the processes that lead to aging. In model organisms, we can use mutagenesis to discover mutations that; increase life span, and hence infer that the wild-type allele limits life span by some means. We have assessed longevity in a collection of 1332 co-isogenic gene-trap; P-element insertion lines and determined changes in life span of each insert line relative to the corresponding control line. Significant lines were determined via two different methods of analysis: A 95% confidence interval was established based on deviations of the mutant life spans from the controls and Dunnett s two tailed t-tests were used to examine differences between mutant and control in each individual block. Based on the 95% confidence interval, 139 inserts displayed an increase in life span and 194 inserts a decrease. Using Dunnett's, 70 lines increased in life span, while 270 decreased in life span. An additional 48 increased longevity lines were close enough to meeting Dunnett s criteria to be considered for additional investigation. Combining these two analyses, we chose 83 inserts associated with increased life span for a secondary screen using an; additional twelve replicates. 58 of these lines remained significant. We have; determined the P-element insertion site for 50 of these lines. Starvation resistance, chill coma recovery time and climbing activity were; measured on the lines remaining significant after the the secondary screen to identify pleiotropic effects. A positive correlation was found for males between life span and starvation resistance as well as between life span and chill coma recovery. Females only displayed a correlation between life span and chill coma recovery, which was negative. None of the lines indicated increased fitness for all phenotypes, indicating there may be some type of trade-off. There also appears to be a lot of pleiotropic variation depending on background and sex. Ten of the lines, all with the same parental background, were chosen for a; half-diallel cross to identify epistasis between the mutants. There were; substantial epistatic interactions between all ten lines. Furthermore, males and females displayed vastly different patterns of epistasis, again indicating major differences in life span regulation between the sexes. Finally, a subset of seven of the lines used in the epistatic study, in; addition to the corresponding parental control, were chosen for microarray; analysis to look for possible pathways and novel genes involved in increasing life span. 1,996 probe sets were significant at a false discovery rate q-value; threshold of q < 0.0001. Tukeys tests were carried out for these probe sets to determine how each of the seven mutant backgrounds differed compared to the control and each other. In addition, each mutant background was compared individually with the control to identify any changes in expression. Gene ontologies were determined for each of the lines to identify over-represented biological functions which would indicate possible longevity pathways. Dozens of pathways were suggested, including several novel pathways. Experiment Overall Design: We used seven mutant lines homozygous for a P-element insertion and a control line. All lines were isogenic other than the P-element insert. Males and females were done separately with two replicates for a total of 32 arrays.
Chips
  • Chip ID: GSM216502 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM216504 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM216501 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM216503 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality

Affymetrix experiment GSE8938

Experiment name Transcription profiling of Drosophila infected with the parasitoid wasps Leptopilina boulardi and L. heterotoma to investigate infection strategies [GSE8938]
Source GEO
Experiment description Although host-parasitoid interactions are becoming well characterized at the organismal and cellular levels, much remains to be understood of the molecular bases for the host immune response and the parasitoids ability to defeat this immune response. Leptopilina boulardi and L. heterotoma, two closely related, highly infectious natural parasitoids of Drosophila melanogaster, appear to use very different infection strategies at the cellular level. Here, we further characterize cellular level differences in the infection characteristics of these two wasp species using newly derived, virulent inbred strains, and then use whole genome microarrays to compare the transcriptional response of Drosophila to each. While flies attacked by the melanogaster group specialist Leptopilina boulardi (strain Lb17) up-regulate numerous genes encoding proteolytic enzymes, components of the Toll and JAK/STAT pathways, and the melanization cascade as part of a combined cellular and humoral innate immune response, flies attacked by the generalist L. heterotoma (strain Lh14) do not appear to initiate an immune transcriptional response at the time points post-infection we assayed, perhaps due to the rapid venom-mediated lysis of host hemocytes (blood cells). Thus, the specialist parasitoid appears to invoke a full-blown immune response in the host, but suppresses and/or evades downstream components of this response. Given that activation of the host immune response likely depletes the energetic resources of the host, the specialist s infection strategy seems relatively disadvantageous. However, we uncover the mechanism for one potentially important fitness tradeoff of the generalist's highly immune suppressive infection strategy. Experiment Overall Design: The parasitoid wasps L. boulardi and L. heterotoma were allowed to attack late second instar D. melanogaster larvae (72 hrs old at 22 C) in the following manner. Nine petri dishes containing 60 fly larvae were each exposed to six experienced L. boulardi (strain Lb17) female wasps for 2 hrs, another nine plates were exposed to five L. heterotoma (strain Lh14) females, and nine control plates were left uninfected. For each of three time points post-infection (2-5 hrs, 9-12 hrs, 21-24 hrs), 40 larvae from three replicate plates were removed and frozen at -80 C for RNA extraction and microarray analysis (3 treatments x 3 time points x 3 replicates = 27 samples total).
Chips
  • Chip ID: GSM226638 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM226648 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM226637 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM226656 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM226646 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: marginal - Quality: low quality
  • Chip ID: GSM226647 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM226657 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM226639 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: present - Quality: high quality
  • Chip ID: GSM226655 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005338
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE9149

Experiment name Transcription profiling of Drosophila untreated males and females [GSE9149]
Source GEO
Experiment description Wild-type laboratory strains of model organisms are typically kept in isolation for many years, with the action of genetic drift and selection on mutational variation causing lineages to diverge with time. Natural populations from which such strains are established, show that gender-specific interactions in particular drive many aspects of sequence level and transcriptional level variation. Here, our goal was to identify genes that display transcriptional variation between laboratory strains of Drosophila melanogaster, and to explore evidence of gender-biased interactions underlying that variability. Experiment Overall Design: Three replicate groups of males and virgin females were collected for each sex and genotype combination. Total RNA was extracted independently for each of the 30 samples (five lines x two sexes x three replicates)
Chips
  • Chip ID: GSM231207 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231205 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231206 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231222 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231228 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231227 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231215 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231225 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231219 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231230 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231220 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231212 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231232 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231217 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231218 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231216 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231233 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231211 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231226 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231214 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231208 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231210 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231229 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231221 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231209 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231213 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231224 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231223 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM231231 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005369
    • Probeset ID: 143546_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Affymetrix experiment GSE9552

Experiment name Transcription profiling of Drosophila w1118 flies treated with different doses of radiation at different time points [GSE9552]
Source GEO
Experiment description To determine what genes are affect to the reduction in mutation frequency by 500 Gy gamma irradiation of Drosophila melanogaster. The strain is w[1118] (a loss of function mutant of compound eye pigment gene white with Canton-S background). Experiment Overall Design: 15 samples are analyzed. The control and four time course (5, 30, 60 and 90min), 3 Biological rep. (A to C).
Chips
  • Chip ID: GSM241756 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality
  • Chip ID: GSM241764 - Annotation by Bgee curators: Anatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv:00005289
    • Probeset ID: 1638398_at - Mapped to gene: FBgn0005564 - Detection flag: absent - Quality: high quality

Hide | TopExpressed Sequence tags

EST library 15893

Library name Exelixis FlyTag CK01 pCDNA-SK+ [15893]
Source Unigene
Library description Random primed, normalized library from mixed stage embryos, imaginal disks, and adult heads.
Annotation by Bgee curatorsAnatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv_root:00000000
EST

EST library 15894

Library name Exelixis FlyTag CK02 pCDNA-SK+ [15894]
Source Unigene
Library description Random primed, normalized library from mixed stage embryos, imaginal disks, and adult heads. Subset of Exelixis FlyTag CK01 clones sequenced from 3' end
Annotation by Bgee curatorsAnatomical structure ID: FBbt:00007001 - Developmental stage ID: FBdv_root:00000000
EST

EST library 19761

Library name AB01 [19761]
Source Unigene
Library description
Annotation by Bgee curatorsAnatomical structure ID: OGEO:000002 - Developmental stage ID: FBdv:00000000
EST

EST library 19762

Library name AB03 [19762]
Source Unigene
Library description
Annotation by Bgee curatorsAnatomical structure ID: OGEO:000002 - Developmental stage ID: FBdv:00000000
EST

EST library 19763

Library name CK01 [19763]
Source Unigene
Library description
Annotation by Bgee curatorsAnatomical structure ID: OGEO:000002 - Developmental stage ID: FBdv:00000000
EST

EST library 19806

Library name CK02 [19806]
Source Unigene
Library description
Annotation by Bgee curatorsAnatomical structure ID: OGEO:000002 - Developmental stage ID: FBdv:00000000
EST

EST library 2294

Library name Drosophila melanogaster adult testis library [2294]
Source Unigene
Library description Testes dissected from 1-5 day adult y[*] w[67c1]/Y males raised at 25oC. RNA isolated using Trizol (Life Technologies) and a single round of Poly(A)+ selection using Oligotex (Qiagen). cDNA library constructed using Stratagene ZAP-cDNA syntesis kit. Oligo dT-primed, size fractionated ~1-6 kb, and directionally cloned at EcoRI and XhoI in Uni-ZAP XR. Following a single round of amplification pBlueScript SK phagemids were mass excised. A distribution channel for clones is being sought, but not currently available. Requests for clones cannot be honored.
Annotation by Bgee curatorsAnatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
EST

EST library 7236

Library name AT Drosophila melanogaster adult testes pOTB7 [7236]
Source Unigene
Library description The mRNA for the testis library was made from testes and seminal vessicles hand dissected from 0-3 day old Ore-R males. RNA kindly provided by the lab of Margaret Fuller. Sized fractionated cDNAs were directly ligated into pOTB7. Plasmid cDNA library.
Annotation by Bgee curatorsAnatomical structure ID: FBbt:00004928 - Developmental stage ID: FBdv:00005369
EST

EST library 9544

Library name RE Drosophila melanogaster normalized Embryo pFlc-1 [9544]
Source Unigene
Library description Library was kindly generated by Piero Carninci at the RIKEN. The library was normalized and excised using Cre recombinase. Plasmid cDNA library.
Annotation by Bgee curatorsAnatomical structure ID: FBbt:00000052 - Developmental stage ID: FBdv:00005289
EST